A prospective multi-centre randomised controlled trial study

A two group blinded randomised trial will be conducted in 88 patients who will be allocated to ToKa or standard HTO. Measurements pre-operation and at 6 months will include assessments of surgical accuracy using X-rays, dynamic assessment, length of operation, self-reported outcome and health resource use. Patients and assessors will be blinded to the treatment allocation.

Knee osteoarthritis (OA) is common, painful, progressive and disabling, and has significant personal and societal burden, particularly in an ageing population. Whilst knee replacement is successful for very late stage disease, it is inappropriate for earlier stages leaving few effective treatments available for patients in the “treatment gap” between symptom free and late-stage arthritis.

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